Description
Proviron is the trade name of the oral androgen mesterolone (1-methyl dihydrotestosterone) created by the pharmaceutical company Schering.
Like dihydrotestosterone, mesterolone has stronger androgenic and weaker anabolic activity, although the ratio of its androgenic to anabolic action is 30-40 to 100-150.
The reason for this is that, like dihydrotestosterone, mesterolone is rapidly broken down to inactive diol metabolites in muscle tissue, where the concentration of the enzyme 3-hydroxysteroid dehydrogenase is high. However, mesterolone has an extremely high affinity for plasma binding proteins such as sex hormone binding globulin (SHBG) and thus enhances the action of other steroids and testosterone by displacing them by binding to SHBG, thus providing greater unbound and active amounts of them.




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